The case study series, conducted in 2021, demonstrate the safety and efficacy of Oxapex when used to manage tissue hypoxia in anaemic dogs. Oxapex has been used in veterinary clinics in New Zealand with resounding success. To date, several dogs of various breeds have received Oxapex with no serious adverse effects. The majority responded very well to Oxapex resulting in significantly improved clinical signs, and were alive and well a week after treatment with Oxapex. The causes of anaemia in these dogs were varied and included haemorrhage due to neoplasia, IMHA and gastric ulcerations.